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Honorary Professor at UCT. His primary research interests are C-type lectin receptors and their role in homeostasis and immunity, with a particular focus on antifungal immunity. His research interests revolve around investigating immune regulation and dysregulation in the context of HIV infection or exposure. He focuses on Immune ontogeny in HIV exposed infants, placental investigations and pre-term birth, and epithelial immunity in the foreskin.

Her Research Unit is involved with clinical research, epidemiology and operational research, and is a treatment site for HIV infected adults and children. Her research interests include HIV vaccine research, microbicide research and other biomedical and behavioural interventions, and she is an investigator in testing two HIV vaccine regimens in late stage clinical development. He has been an author on over manuscripts in the field of infectious diseases and has an extensive track record in infectious diseases research and practice covering clinical, laboratory and epidemiological aspects.

He is an HIV and TB immunologist focused on studying the immune response to these pathogens in affected tissues, and how this relates to what can be observed from the blood.